Nan Cai Selected Research

Pimozide (Orap)

9/2019	Antipsychotic agent pimozide promotes reversible proliferative suppression by inducing cellular quiescence in liver cancer.
3/2017	The neuroleptic drug pimozide inhibits stem-like cell maintenance and tumorigenicity in hepatocellular carcinoma.
1/2017	The STAT3 inhibitor pimozide impedes cell proliferation and induces ROS generation in human osteosarcoma by suppressing catalase expression.
1/2016	The antipsychotic drug pimozide inhibits cell growth in prostate cancer through suppression of STAT3 activation.

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Nan Cai Research Topics

Disease

4	Hepatocellular Carcinoma (Hepatoma) 05/2021 - 01/2016
3	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 02/2020
3	Neoplasms (Cancer) 05/2021 - 01/2017
2	Inflammation (Inflammations) 07/2021 - 01/2015
2	Liver Neoplasms (Liver Cancer) 09/2019 - 03/2017
2	Poisoning 10/2018 - 08/2018
2	Prostatic Neoplasms (Prostate Cancer) 01/2017 - 01/2016
1	Disease Resistance 06/2022
1	Starvation 01/2022
1	Rib Fractures (Rib Fracture) 01/2022
1	Emergence Delirium 08/2021
1	Sleep Deprivation 08/2021
1	Acute Lung Injury 07/2021
1	Fibrosis (Cirrhosis) 07/2021
1	Pneumonia (Pneumonitis) 07/2021
1	Liver Cirrhosis (Hepatic Cirrhosis) 07/2021
1	Adenocarcinoma of Lung 05/2021
1	Neoplasm Metastasis (Metastasis) 05/2021
1	Infections 12/2020
1	Hemorrhage 12/2020
1	Heart Arrest (Cardiac Arrest) 12/2020
1	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2020
1	Non-alcoholic Fatty Liver Disease 12/2019
1	Pulmonary Edema 10/2018
1	Lung Injury 10/2018
1	Type 2 Diabetes Mellitus (MODY) 08/2018
1	Coronary Disease (Coronary Heart Disease) 08/2018
1	Hypertension (High Blood Pressure) 08/2018
1	Respiratory Insufficiency (Respiratory Failure) 08/2018
1	Osteosarcoma (Osteogenic Sarcoma) 01/2017
1	Cognitive Dysfunction 09/2016

Drug/Important Bio-Agent (IBA)

4	Antipsychotic Agents (Antipsychotics)IBA 09/2019 - 01/2016
4	Pimozide (Orap)FDA Link 09/2019 - 01/2016
3	Pharmaceutical PreparationsIBA 09/2019 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 07/2021 - 10/2018
2	Interleukin-6 (Interleukin 6)IBA 07/2021 - 10/2018
2	PesticidesIBA 10/2018 - 08/2018
1	carvacrolIBA 06/2022
1	LigninIBA 06/2022
1	macelignanIBA 01/2022
1	ChlorophyllIBA 01/2022
1	MelatoninIBA 08/2021
1	genipinIBA 08/2021
1	LipopolysaccharidesIBA 07/2021
1	TNF Receptor-Associated Factor 3IBA 07/2021
1	MicroRNAs (MicroRNA)IBA 07/2021
1	Adenosine Triphosphate (ATP)IBA 07/2021
1	CurcuminIBA 07/2021
1	Transfer RNA (tRNA)IBA 05/2021
1	RNA (Ribonucleic Acid)IBA 05/2021
1	Small Cytoplasmic RNAIBA 05/2021
1	Long Noncoding RNAIBA 05/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2020
1	tau Proteins (tau Protein)IBA 02/2020
1	Sirtuin 1IBA 12/2019
1	LipidsIBA 12/2019
1	mangostinIBA 12/2019
1	OrganophosphatesIBA 10/2018
1	DichlorvosIBA 10/2018
1	Advanced Oxidation Protein Products (AOPP)IBA 10/2018
1	AcetylcholinesteraseIBA 10/2018
1	XuebijingIBA 10/2018
1	Hypnotics and Sedatives (Sedatives)IBA 08/2018
1	ParaquatIBA 08/2018
1	CatalaseIBA 01/2017
1	Fluorouracil (Carac)FDA LinkGeneric 01/2017
1	ginsenoside Rg1IBA 09/2016
1	AntioxidantsIBA 09/2016
1	Glycogen Synthase (Synthase I)IBA 09/2016
1	Neuroprotective AgentsIBA 09/2016
1	Phosphatidylinositols (Phosphatidylinositol)IBA 09/2016
1	Isoflurane FDA LinkGeneric 09/2016
1	Phosphotransferases (Kinase)IBA 01/2015

Therapy/Procedure

2	Therapeutics 12/2020 - 09/2019
1	Analgesia 01/2022
1	Ambulatory Surgical Procedures (Outpatient Surgery) 08/2021
1	Intravenous Injections 05/2021
1	Intraperitoneal Injections 10/2018
1	Length of Stay 08/2018
1	Artificial Respiration (Mechanical Ventilation) 08/2018
1	Drug Therapy (Chemotherapy) 03/2017
1	Anesthesia 09/2016